Open AccessEffects of the aqueous and hexane extracts of <i>Mondia whitei</i> on the sexual behaviour and some fertility parameters of sexually inexperienced male rats
Author(s) -
Pierre Watcho,
Fabien Zelefack,
T. B. Nguelefack,
Silvà ̈re Ngouela,
Phélix Bruno Telefo,
Pièrre Kamtchouing,
Etienne Tsamo,
Albert Kim
Publication year - 2007
Publication title -
african journal of traditional complementary and alternative medicines
Language(s) - English
Resource type - Journals
eISSN - 2505-0044
pISSN - 0189-6016
DOI - 10.4314/ajtcam.v4i1.31190
Subject(s) - fertility , ejaculation , libido , medicine , physiology , endocrinology , biology , population , environmental health
The effects of Mondia whitei Hook (Skeels) were studied on the sexual behaviour and some fertility parameters of sexually inexperienced male rats. Animals were orally administered 100 mg/kg and 500 mg/kg of body weight (b.w) of either the aqueous or the hexane extracts of Mondia whitei whilst the control group received 10 mL/kg b.w of 0.3% Tween 80 once/day for 14 days. Their sexual behaviour was monitored on days 0, 1, 7 and 14 days of treatment and 14 days post-treatment. Some fertility parameters (index libido, quantal pregnancy, fertility index) of the treated rat were evaluated on day 13 of treatment by pairing it overnight with two proestrus females. Results showed that Mondia whitei extracts significantly (p<0.001) reduced the mount latency and the hexane extract was found to be more efficient than the aqueous extract. The treatment had no significant effect (p>0.05) on intromission, ejaculation and erection. The fertility of the animals remained unaffected. It's concluded that Mondia whitei had sexual enhancement of the sexually inexperienced male rats.