Open AccessEstrogenic and pregnancy interceptory effects of <i>Achyranthes aspera</i> Linn. root
Author(s) -
Neeru Vasudeva,
Swati Sharma
Publication year - 2007
Publication title -
african journal of traditional complementary and alternative medicines
Language(s) - English
Resource type - Journals
eISSN - 2505-0044
pISSN - 0189-6016
DOI - 10.4314/ajtcam.v4i1.31185
Subject(s) - achyranthes aspera , traditional medicine , abortifacient , amaranthaceae , herb , body weight , biology , pharmacology , medicine , chemistry , pregnancy , botany , medicinal herbs , abortion , endocrinology , alternative medicine , pathology , genetics
Achyranthes aspera Linn. (Amaranthaceae) is an abundant indigenous herb in India. It is traditionally being used as an abortifacient. Four successive solvent extracts of the root were screened for antifertility activity in female albino rats. The chloroform and ethanol extracts exhibited 100% anti-implantation activity when given orally at 200 mg/kg body weight. Both the extracts at the dose of 200 mg/kg body weight also exhibited estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity.