Open AccessThe evaluation of vancomycin-resistant enterococci and carbapenamase producing Klebsiella colonization among ICU-Hospitalized Patients
Author(s) -
Gökhan Karaşin,
Yasemin Bayram,
Mehmet Parlak,
Cenk Aypak,
Mustafa Barış Akgül,
Hüseyin Güdücüoğlu
Publication year - 2021
Publication title -
african health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 44
eISSN - 1729-0503
pISSN - 1680-6905
DOI - 10.4314/ahs.v21i4.20
Subject(s) - medicine , carriage , colonization , enterococcus faecium , vancomycin resistant enterococcus , klebsiella pneumoniae , enterococcus , vancomycin , vancomycin resistant enterococci , intensive care , intensive care unit , antibiotics , microbiology and biotechnology , intensive care medicine , staphylococcus aureus , bacteria , biology , escherichia coli , biochemistry , genetics , pathology , gene
Background: Multi-drug resistant organisms, especially Vancomycin-Resistant Enterococcus (VRE) and Carbapenam Resistant Klebsiella pneumoniae (KPC), are serious health threat. Early detection of resistant bacteria colonization amongpatients in intensive care units (ICUs) not only enables effective treatment but more importantly prevents disease and limits transmission. Therefore, we aimed to to assess the frequency of VRE and KPC colonization via rectal swab sampling.
Methods: The study was carried out in ICUs of a tertiary hospital. Two rectal swab samples were collected within the first 24 hours of admission and another one was taken every subsequent 15 days to test for for VRE and KPC carriage.
Results: A total 316 rectal swab samples taken from 230 patients. Forty-seven patients were screened at least 2 times. 183 patients were not further screened due to discharge, exitus or transfer to other wards. Thirty-six patients (16%) were determinedto be VRE (+). The most frequently isolated strain was E. faecium (80.5%) and its most common genotype was VanA (87.5%). Seven patients (3%) were identified as KPC (+). OXA-48 type crbapenamase was confirmed in all KPC isolates.
Conclusion: This study shows that VRE and KPC colonization continues to be a serious threat in ICUs.
Keywords: Carbapenam resistant klebsiella pneumoniae; vancomycin-resistant enterococci; intensive care units.