Open AccessRelationship between disease severity and folate status of children with sickle cell anaemia in Enugu, South East Nigeria
Author(s) -
Uchenna C Nnajekwu,
Chukwubike O Nnajekwu,
Vivian Ozoemena Onukwuli,
Ndubuisi A Uwaezuoke,
Osita U Ezenwosu,
AN Ikefuna,
IJ Emodi
Publication year - 2021
Publication title -
african health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 44
eISSN - 1729-0503
pISSN - 1680-6905
DOI - 10.4314/ahs.v21i2.35
Subject(s) - medicine , disease , anemia , pediatrics , odds ratio , population , fetal hemoglobin , sickle cell anemia , population study , pregnancy , fetus , environmental health , biology , genetics
Repeated crises in children with sickle cell anaemia (SCA), which is a manifestation of disease severity, results in depletion of their minimal tissue folate stores, with higher likelihood of folate deficiency. The study aimed to determine the relationship between disease severity and the folate status of children with SCA attending University of Nigeria Teaching Hospital (UNTH), Enugu.