
Burden of iron overload among non-chronically blood transfused preschool children with sickle cell anaemia
Author(s) -
Akodu Samuel Olufemi,
Adekanmbi Abiodun Folashade,
Ogunlesi Tinuade Adetutu
Publication year - 2021
Publication title -
african health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 44
eISSN - 1729-0503
pISSN - 1680-6905
DOI - 10.4314/ahs.v21i2.34
Subject(s) - medicine , transferrin saturation , haemolysis , ferritin , blood transfusion , transferrin , iron deficiency , serum iron , sickle cell anemia , anemia , immunology , pediatrics , serum ferritin , physiology , disease
Sickle cell disease is the commonest genetic disorder of haemoglobin due to inheritance of mutant haemoglobin genes from both parents. The disorder is characterized by chronic haemolysis which results in increased availability of iron from red blood cell destructions.