Open AccessTransient bone marrow hypoplasia preceding T-Cell acute lymphoblastic leukemia: a case report
Author(s) -
Ernest Naturinda,
P.S. George,
Joseph Ssenyondwa,
Deogratias Bakulumpagi,
Joseph Lubega,
Peter Wasswa
Publication year - 2021
Publication title -
african health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 44
eISSN - 1729-0503
pISSN - 1680-6905
DOI - 10.4314/ahs.v21i2.25
Subject(s) - pancytopenia , medicine , hypoplasia , bone marrow , pathology , acute leukemia , dysplasia , leukemia , immunology
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and is characterised by hyperproliferation of malignant lymphocytes in the bone marrow. Rarely, ALL may be preceded by a period of pancytopenia and bone marrow hypoplasia which spontaneously recovers. This phenomenon, which has not before been described in T-cell ALL, is referred to as transient bone marrow hypoplasia.