Open AccessAllium sativum aqueous extract does not have chemo-protective effect on etoposide induced therapy-related DNA damage leading to Acute Myeloid Leukemia in albino-wistar rats
Author(s) -
Ugochi F Ndiokwelu,
L.A. Ogunkanmi,
J. B. Minari,
Ijeoma C Uzoma
Publication year - 2021
Publication title -
african health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 44
eISSN - 1729-0503
pISSN - 1680-6905
DOI - 10.4314/ahs.v21i2.24
Subject(s) - etoposide , medicine , myeloid leukemia , bone marrow , dna fragmentation , allium sativum , leukemia , sativum , aqueous extract , decoction , pharmacology , traditional medicine , chemotherapy , apoptosis , biology , botany , biochemistry , programmed cell death
Therapy-related acute myeloid leukemia (t-AML) is a well-recognized clinical syndrome occurring in a significant fraction of patients who have undergone previous chemotherapy for a solid tumour.