Open AccessMonocyte-to-HDL-cholesterol ratio is associated with Ascending Aorta Dilatation in Patients with Bicuspid Aortic Valve
Author(s) -
Burak Açar,
Çağrı Yayla,
Murat Gül,
Mustafa Karanfil,
Sefa Ünal,
Fatih Mehmet Uçar,
Serdar Kuyumcu,
Ahmet Göktuğ Ertem,
Yasin Özen,
Mustafa Bilal Özbay,
Özcan Özeke,
Sinan Aydoğdu
Publication year - 2021
Publication title -
african health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 44
eISSN - 1729-0503
pISSN - 1680-6905
DOI - 10.4314/ahs.v21i1.14
Subject(s) - bicuspid aortic valve , medicine , cardiology , ascending aorta , aorta , aortic valve , population , bicuspid valve , environmental health
Background The importance of monocyte count-to-HDL-cholesterol ratio (MHR) in cardio- vascular diseases has been shown in various studies. Ascending aortic dilatation (AAD) is a common complication in the patients with bicuspid aortic valve. In this study, we aimed to investigate the relationship between MHR and the presence of aortic dilatation in the patients with bicuspid aortic valve. Methods The study population included totally 347 patients with bicuspid aortic valve.169 patients with aortic dilatation (ascending aorta diameter ≥ 4.0 cm) and 178 patients with no aortic dilatation. Echocardiographic and laboratory measurement was done and compared between groups. Results The mean age of the participants was 44.7 ± 15.4 years and average ascending aorta diameter was 3.2 ± 0.3 cm in dilatation negative group and 4.4 ± 0.4 cm in positive group. MHR was significantly increased in in patients with aortic dilatation. MHR and uric acid level was independently associated with the presence of aortic dilatation in the patients with bicuspid aortic valve. Conclusion We found a significant relationship between MHR and aortic dilatation in the patients with bicuspid aortic valve.