Open AccessPrevalence and associated factors of intestinal parasite infection by HIV infection status among asymptomatic adults in rural Gabon
Author(s) -
Jeanne Vanessa Koumba Lengongo,
Bedrich Pongui Ngondza,
Bridy Moutombi Ditombi,
Noé Patrick M’Bondoukwé,
Jacques Mari Ndong Ngomo,
Arnaud Mongo Delis,
Princilia Bouyi Lekounga,
Marielle Karine Bouyou-Akotet,
Denise Patricia Mawili-Mboumba
Publication year - 2020
Publication title -
african health sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.391
H-Index - 44
eISSN - 1729-0503
pISSN - 1680-6905
DOI - 10.4314/ahs.v20i3.5
Subject(s) - medicine , asymptomatic , intestinal parasite , population , cross sectional study , immunology , human immunodeficiency virus (hiv) , logistic regression , helminths , pathology , environmental health
Intestinal parasites infections are endemic in Gabon. Nevertheless, they are rarely described in people living with HIV (PLHIV).
Objective: The frequency of intestinal parasite infection was estimated and compared between HIV-positive and HIV un- infected individuals in Gabon; factors associated with intestinal parasites were also analysed.
Material and Methods: Using a cross-sectional study design sociodemographic data, life style habits, antiretroviral therapy, cotrimoxazole use and CD4 cell count were recorded.. Stool samples from participants living in Koulamoutou and Oyem were analysed using microscopy. Chi-squared or fisher’s exact tests and logistic regression were performed.
Results: Among participants (n=332), female gender was predominant (73.7%; n=135/183) and the median age was 45 [33-57] years old. Among 183 samples, 53.6% (n = 98/183) were infected by intestinal parasites. The proportion was higher (72.1%) in HIV negative participants compared to PLHIV (42.6%) (p 70.0%).
Conclusion: Prevalence of intestinal parasites is higher in seronegative participants but polyparasitism is more frequent in PLHIV. Strategies are focused on HIV negative population, but this study shows the importance of sensitization for PLHIV to improve their quality of life.
Keywords: Intestinal parasites; Human immunodeficiency virus; cotrimoxazole; CD4 cell; Gabon.