Open AccessDirect molecular detection of Mycobacterium tuberculosis complex from clinical samples - An adjunct to cultural method of laboratory diagnosis of tuberculosis
Author(s) -
O. A. Terry Alli,
Olusoga Alaka
Publication year - 2011
Publication title -
north american journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2250-1541
pISSN - 1947-2714
DOI - 10.4297/najms.2011.3281
Subject(s) - ethyl acetate , rutin , ic50 , mycobacterium tuberculosis , chromatography , mtt assay , medicine , flavonoid , antibacterial activity , in vitro , tuberculosis , traditional medicine , chemistry , biochemistry , biology , pathology , bacteria , genetics , antioxidant
Tuberculosis, a communicable disease with significant morbidity and mortality, is the leading cause of death in the world from bacterial infectious disease. Because of its public health importance, there is need for rapid and definitive method of detecting the causative organism. Several approaches have been attempted, but the molecular methods, especially Polymerase Chain Reaction assays are the most promising for rapid detection of Mycobacterium tuberculosis complex from clinical samples.