Open AccessSimilarities and differences between Behçet's disease and Crohn's disease
Author(s) -
Veli Yazısız
Publication year - 2014
Publication title -
world journal of gastrointestinal pathophysiology
Language(s) - English
Resource type - Journals
ISSN - 2150-5330
DOI - 10.4291/wjgp.v5.i3.228
Subject(s) - medicine , pathognomonic , behcet's disease , disease , crohn's disease , behcet disease , epidemiology , inflammatory bowel disease , dermatology , pathology , gastroenterology
Behçet's disease (BD) is a chronic inflammatory condition with multisystem involvement. Approximately 10%-15% of patients present with gastrointestinal involvement. Involved sites and the endoscopic view usually resemble Crohn's disease (CD). In addition to intestinal involvement, oral mucosa, the eyes, skin, and joints are commonly affected. No pathognomonic laboratory test is available for the diagnosis of either disease. Management approaches are also similar in various aspects. Differentiating BD from CD is highly challenging. In this article, the similarities and differences between BD and CD in terms of epidemiology, etiopathogenesis, clinical and imaging findings, and histopathological and therapeutic approaches are reviewed.