Malignite ile ilişkili genodermatozlar

The cutaneous features of some genetic diseases that manifest during childhood might be the first signs of predisposition to cancer; therefore, early recognition of such clinical findings as well as necessary follow-up are vital. This review focuses in particular on nevoid basal cell carcinoma, Cowden syndrome, neurofibromatosis type 1, tuberous sclerosis, Peutz-Jegher’s syndrome, dyskeratosis congenita, and xeroderma pigmentosum.These genodermatoses, are characterised by predisposition to skin cancer or cancer in other organs; as such this review aimed to highlight their diagnostic clinical features.\u