Open AccessEvaluating the Glucantime Concentration for the <i>ex vivo</i> Glial Cell Model of Antimony-resistant <i>Leishmania tropica</i> Amastigotes
Author(s) -
Orçun Zorbozan,
Vedat Evren,
Mehmet Harman,
Ahmet Özbilgin,
Özlem Yılmaz,
Nevın Turgay
Publication year - 2021
Publication title -
türkiye parazitoloji dergisi/türkiye parazitoloji dergisi
Language(s) - English
Resource type - Journals
eISSN - 2146-3077
pISSN - 1300-6320
DOI - 10.4274/tpd.galenos.2021.57966
Subject(s) - amastigote , ex vivo , leishmania tropica , in vivo , leishmania , in vitro , microbiology and biotechnology , chemistry , leishmaniasis , pharmacology , biology , cutaneous leishmaniasis , immunology , biochemistry , parasite hosting , world wide web , computer science
Because the protocols used in the treatment of leishmaniasis can be toxic and have many limitations, such as the development of resistance against such protocols, new treatment options are needed, especially against resistant patients. Ex vivo models may be a good source for evaluating new drug options for patients with antimony-resistant parasites. This study aimed to evaluate the Glucantime concentration for our ex vivo glial cell amastigote model we had defined in previous work.