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Cutaneous Leishmaniasis with Mucosal Involvement
Author(s) -
Mehmet Çabalak,
Gülnaz Çulha,
Tayibe Bal,
Tuğba Kaya,
Ebru Çelik
Publication year - 2021
Publication title -
türkiye parazitoloji dergisi/türkiye parazitoloji dergisi
Language(s) - Uncategorized
Resource type - Journals
eISSN - 2146-3077
pISSN - 1300-6320
DOI - 10.4274/tpd.galenos.2021.21931
Subject(s) - leishmaniasis , cutaneous leishmaniasis , dermatology , medicine , leishmania , immunology , computer science , world wide web , parasite hosting
Leishmaniasis is a protozoan parasitic disease transmitted to humans by infected female sand flies. Turkey has received more than three million immigrants from Syria because of the civil war and political instability. This study reported cases of two patients, who were from Syria and lived in Hatay, with cutaneous leishmaniasis and mucosal involvement. Two patients presented to the infectious diseases clinic with a complaint of facial lesions and were subsequently referred to the parasitology department laboratory. Smears were prepared from the lesions, stained with Giemsa and examined under a microscope. Moreover, aspirates taken from the patients' lesions were inoculated into the modified Novy-MacNeal-Nicolle medium. The diagnosis was made when amastigotes were detected in both smears. Proliferation of promastigotes was observed in one of the clinical specimens inoculated on the medium. By PZR-RFLP, Leishmania tropica were detected in the isolate. Both patients were treated with amphotericin B. One patient was treated again with a pentavalent antimony compound because of the recurrence of the lesion.

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