Open AccessThe Efficacy of Hydroalcoholic Extracts of Prosopis farcta Against <i>Leishmania major</i>
Author(s) -
Mohammad Hasan Namaei,
Rahmat Solgi,
Toktem Rajaii,
Ebrahim Shafaie,
Mehdi Karamian,
Gholamreza Hatam,
Davoud Tasa,
Seyed Mohammad Riahi
Publication year - 2021
Publication title -
türkiye parazitoloji dergisi/türkiye parazitoloji dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.207
H-Index - 18
eISSN - 2146-3077
pISSN - 1300-6320
DOI - 10.4274/tpd.galenos.2020.6956
Subject(s) - amastigote , cytotoxicity , leishmania , traditional medicine , ic50 , leishmaniasis , pharmacology , intracellular , biology , chemistry , in vitro , medicine , immunology , biochemistry , parasite hosting , world wide web , computer science
Cutaneous leishmaniasis caused by Leishmania major ( L. major ) is an endemic disease in Iran. The current reference drugs, including Glucantime, possess high toxicity in addition to some side-effects. Therefore, there is a growing interest in exploring biomedical plants. The goal of the present study was to evaluate the anti-leishmanial activity and cytotoxicity of hydroalcoholic extracts from Prosopis farcta ( P. farcta ) over promastigote and amastigote forms.