Open AccessComparison of <i>in vitro</i> Resistance of Wild <i>Leishmania</i> İsolates, Which are Resistant to Pentavalent Antimonial Compounds, Against Drugs Used in the Treatment of Leishmaniasis
Author(s) -
Ahmet Özbilgin,
İbrahim Çavuş,
Tuğba Kaya,
Ahmet Yıldırım,
Mehmet Harman
Publication year - 2020
Publication title -
türkiye parazitoloji dergisi/türkiye parazitoloji dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.207
H-Index - 18
eISSN - 2146-3077
pISSN - 1300-6320
DOI - 10.4274/tpd.galenos.2019.6661
Subject(s) - leishmania , chemistry , pharmacology , biology , computer science , world wide web , parasite hosting
Meglumine antimoniate (Glucantime ® ) and Sodium stibogluconate (Pentostam ® ) are used for the treatment of cutaneous leismaniasis in Turkey. There is a reported resistance to these drugs in recent years. The aim of the present study was to compare the in vitro sensitivities of resistant Leishmania isolates against Amphotericin B, Miltefosine, Meglumine Antimoniate, Paromomycin and Sodium Stibogluconate.