Open AccessChanges in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran
Author(s) -
Bibi Razieh Hosseini Farash,
Seyed Ali Akbar Shamsian,
Masoud Mohajery,
Abdolmajid Fata,
Fatemeh Sadabadi,
Fariba Berenji,
Pietro Mastroeni,
Elham Poustchi,
Elham Moghaddas,
Ghodratollah Salehi Sangani,
Gholamreza Farnoosh
Publication year - 2020
Publication title -
türkiye parazitoloji dergisi/türkiye parazitoloji dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.207
H-Index - 18
eISSN - 2146-3077
pISSN - 1300-6320
DOI - 10.4274/tpd.galenos.2019.6137
Subject(s) - leishmania tropica , leishmania , cutaneous leishmaniasis , leishmania major , leishmaniasis , epidemiology , incidence (geometry) , veterinary medicine , medicine , immunology , pathology , parasite hosting , physics , optics , world wide web , computer science
The province of Khorasan-Razavi in the North East of Iran is an endemic area for anthroponotic cutaneous leishmaniasis (ACL caused mainly by Leishmania tropica ) and zoonotic cutaneous leishmaniasis (ZCL caused mainly by Leishmania major ). Based on clinical signs, some cities were considered as ACL foci while others were considered to be endemic for ZCL. This paper reviews studies performed on patients diagnosed with cutaneous leishmaniasis (CL) via the use of direct slide examination, ELISA, electrophoresis isoenzyme, RAPD PCR and PCR in Mashhad; the study also includes cases of CL in other cities of the Khorasan-Razavi province where only PCR used as a diagnostic tool. The data show that both Leishmania tropica and Leishmania major caused CL in most of the cities investigated. Our review shows that Leishmania major was found in areas where ACL is prevalent and Leishmania tropica was observed in areas with high incidence of ZCL. This distribution represents a major change in the epidemiological pattern of Leishmania in the Khorasan-Razavi province.