Polypharmacy in Osteoporosis Patients

Objective: In this study, it was aimed to determine the rates of multiple drug use in the patients with osteoporosis as well as the use of\uddrugs affecting bone metabolism and balance.\udMaterials and Methods: We included outpatients from Physical Medicine and Rehabilitation Policlinics diagnosed with primary or secondary\udosteoporosis between January 2014 and May 2014. Written consent of the participants was obtained. Data of the first 1000 patients who\udagreed to participate in the study were evaluated. Data regarding age, history, drugs currently being used and newly initiated were recorded.\udThe drugs that affect bone metabolism were determined. The drugs that heva side effects including dizziness, somnolence, distractibility,\uddecrease in the visual acuity, orthostatic hypotension and ototoxicity and were recorded because these can cause a balance disorder.\udResults: In this study, 64% of the participants were on five or more drugs. The most commonly used drugs were analgesics (65.4%), antihypertensives\ud(52.6%), and drugs for digestive system (37.3%). We found that 65.5% of the participants were using drugs that may have\udside effects on bone metabolism and 93.7% were using drugs that may have side effects on balance.\udConclusion: Multi-drug use and drug interactions should be considered during the treatment of osteoporosis and the drugs used should be\udrecorded. Drugs that affect bone metabolism should only be used over the short term. Also, patients should be informed about side effects\udthat might affect visuality, somatosensorial system and vestibular system and their daily activities should be regulated. (Turkish Journal of\udOsteoporosis 2015;21: 5-9