Open AccessOsteopenisi Olan Ankilozan Spondilitli Hastalarda Kemik Mineral Yoğunluğu ile Hastalık Aktivitesi Arasındaki İlişkinin Değerlendirilmesi
Author(s) -
Hayal Güler,
Nilgün Üstün,
Veli Enes Bolaç,
Abdullah Erman Yağız,
Ayhan Mansuroğlu,
Erhan Yengil,
Ayşe Dicle Turhanoğlu
Publication year - 2013
Publication title -
türk osteoporoz dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.108
H-Index - 5
ISSN - 2146-3816
DOI - 10.4274/tod.29290
Subject(s) - medicine
Summary\udAim: Ankylosing Spondylitis (AS) is a chronic inflammatory disease. Spinal osteopenia is common in AS, probably due to immobility and local\udcytokine release. In this study, we evaluated the relationship between bone mineral density and disease activity in Ankylosing Spondylitis\udpatients with osteopenia.\udMaterial and Methods: Sixty one AS patients (26F, 35M) were enrolled in this study. The disease duration, morning stiffness, Schober tests,\udErythrocyte Sedimentation Rate (ESR) and C Reactive Protein (CRP) were analyzed and recorded. Disease activity was evaluated by Bath Ankylosing\udSpondylitis Disease Activity Index (BASDAI). Bone mineral density (BMD) was measured by using GE/LUNAR DPX PRO equipment.\udResults: The mean age and disease duration of the patients were 38.67±10.81 and 7.87±7.09 year. There was osteopenia in 34 (%55.7) patients.\udSpine and femur BMD values of this patients were 1.03±0.16 and 0.88±0.09. BMD measurements of 27 (%44.3) patient were found normally.\udSpine and femur BMD values of this patients were 1.20±0.11 and 1.11±0.15. There was not statistically significant difference between osteopenia\udand normal group in ESR, CRP, and BASDAI values (p>0.05). There was not correlation between BMD values and ESR, CRP, and BASDAI values\udin osteopenia group (p>0.05).\udConclusion: In our study, we did not find relationship between bone mineral density and disease activity in AS patients with osteopenia.\ud(Turkish Journal of Osteoporosis 2013;19: 28-31