Reproduktif Faktörlerin Kemik Mineral Dansitometresi Üzerine Etkileri

Aim: To determine the effects of reproductive factors on bone mineral density (BMD) in postmenopausal women.\udMaterials and Methods: A total of 1196 postmenopausal women with BMD (g/cm2) measurements at lumbar vertebra (LS) and femur neck\ud(FN) were enrolled. Demographic, reproductive characteristics and Body Mass Index (BMI) of patients were defined. In order to define BMD\udrelated factors, multiple regression analysis was employed.\udResults: Main results were as follows: mean age= 59.97±8.56 yrs; weight= 73.49±13.06 kg; BMI= 29.25±5.22kg/m², age of menarche=\ud14.00±1.64 yrs; number of deliveries 4.22±2.09; total breastfeeding duration= 60.77±38.80 months; number of breastfeeding per day=\ud8.23±3.91; menopausal age= 47.12±4.22 yrs; duration of menopause= 12.80±9.10 yrs; LS BMD= 0.993±0.171 gr/cm2; FN BMD 0.844±0.14\udgr/cm2. There were negative correlations between LS BMD and FN BMD values and age, menopause duration, total breastfeeding duration, and\udnumber of breastfeeding per day. There were positive correlations between LS and FN BMD values, and weight and BMI scores. Additionally,\udthere were negative correlations between LS and FN BMD values, and age of menarche and number of deliveries. In linear stage regression\udanalysis, weight, number of breastfeeding per day, postmenopausal duration, duration of total breastfeeding and age of menarche were defined\udas the most significant predictors for LS BMD, whereas weight, postmenopausal duration and number of breastfeeding per day were defined as\udthe most significant predictors for FN BMD.\udConclusion: LS and FN BMD in postmenopausal women are related to reproductive factors, so reproductive factors should also be considered\udin the evaluation of risk factors in postmenopausal women. (Turkish Journal of Osteoporosis 2012;18:8-12