Open Access<i>In Vitro</i> Anti-Leishmanial Activity of Glucosinolate Fraction from <i>Alyssum linifolium</i> Steph. ex Willd (Brassicaceae)
Author(s) -
Fatemeh Mirzaee,
Roghiyeh Faridnia,
Mahdi Fakhar,
Hamed Kalani,
Somayeh Shahani
Publication year - 2023
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2022.78027
Subject(s) - amastigote , glucosinolate , brassicaceae , leishmania , chemistry , biology , botany , traditional medicine , biochemistry , brassica , medicine , parasite hosting , world wide web , computer science
The intracellular parasitic protozoan, Leishmania spp., causes several forms of diseases in humans. Cytotoxicity and emergence of new strains resistance to the current anti-leishmanial drugs have encouraged researchers to focus on new resources. Glucosinolates (GSL) are found mainly in the Brassicaceae family with potential cytotoxic and anti-parasitic properties. The present study reports in vitro antileishmanial activity of the GSL fraction from Alyssum linifolium seeds against Leishmania major .