Open AccessMolecular Docking Studies to Identify Promising Natural Inhibitors Targeting SARS-CoV-2 Nsp10-Nsp16 Protein Complex
Author(s) -
Arun Bhardwaj,
Swati Sharma,
Sandeep Kumar Singh
Publication year - 2022
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2021.56957
Subject(s) - druggability , natural product , in silico , drug discovery , docking (animal) , pharmacology , theaflavin , chemistry , population , biology , computational biology , biochemistry , medicine , polyphenol , nursing , environmental health , gene , antioxidant
Unavailability of potential drugs/vaccines in the outbreak of the pandemic severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) have devastated the human population globally. Several druggable targets have been analyzed against different viral proteins such as the spike protein. The study aims to explore the potential of natural compounds as an effective drug against a novel nsp10-nsp16 complex of SARS-CoV-2 using in silico approaches.