Open AccessDevelopment and Validation of Chromatographic and Spectrophotometric Methods for the Quantitation of Rufinamide in Pharmaceutical Preparations
Author(s) -
Habibur Rahman,
Sk Manirul Haque
Publication year - 2022
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2021.37043
Subject(s) - chromatography , high performance liquid chromatography , chemistry , detection limit , acetonitrile , pharmaceutical formulation , dosage form , accuracy and precision , methanol , mathematics , statistics , organic chemistry
Two optimized and validated high performance liquid chromatography (HPLC) and spectrophotometric methods are proposed. The developed methods were quantified with high sensitivity, accuracy, and precision at low concentrations to determine rufinamide (RUF) in active pharmaceutical ingredients (API) and pharmaceutical preparations.