Determination of the Physicochemical Properties of Piroxicam | Zendy

Mustafa Çelebi̇er | Zendy; Merve Nenni | Zendy; Ozan Kaplan | Zendy; Emrah Akgeyik | Zendy; Mustafa Sinan Kaynak | Zendy; Selma Şahin | Zendy

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Determination of the Physicochemical Properties of Piroxicam

Author(s) -

Mustafa Çelebi̇er,

Merve Nenni,

Ozan Kaplan,

Emrah Akgeyik,

Mustafa Sinan Kaynak,

Selma Şahin

Publication year - 2020

Publication title -

turkish journal of pharmaceutical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.241

H-Index - 14

eISSN - 2148-6247

pISSN - 1304-530X

DOI - 10.4274/tjps.galenos.2019.82335

Subject(s) - high performance liquid chromatography , chemistry , chromatography , partition coefficient , piroxicam , spectrophotometry , analytical chemistry (journal) , acid dissociation constant , acetonitrile , aqueous solution , organic chemistry , medicine , alternative medicine , pathology

The aim of this study was to determine the acid dissociation constant (pKa) of piroxicam using high performance liquid chromatography (HPLC) and ultraviolet-visible (UV-Vis) spectrophotometry, and to determine the partition coefficient (Log P), distribution coefficient (Log D), and "Log kw" values of piroxicam using HPLC.

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