Open AccessGlobal DNA Hypomethylation and <i>Rassf1a</i> and <i>c-myc</i> Promoter Hypermethylation in Rat Kidney Cells after Bisphenol a Exposure
Author(s) -
Pınar TuzcuoĞlu,
Sibel Özden
Publication year - 2020
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2019.57983
Subject(s) - dna methylation , microbiology and biotechnology , methylation , cpg site , bisphenol a , promoter , chemistry , kidney , dna , epigenetics , gene expression , gene , biology , biochemistry , endocrinology , organic chemistry , epoxy
Bisphenol A (BPA) is a synthetic monomer used in the production of polycarbonate and an environmental contaminant with endocrine disrupting properties. BPA release from plastic carriers is thought to cause high amounts of exposure, which result in high risk to human and environment health.