Open AccessAntimicrobial Activities of Some Pyrazoline and Hydrazone Derivatives
Author(s) -
Begüm Evranos Aksöz,
Suna Sibel Gürpınar,
Müjde Eryılmaz
Publication year - 2020
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2019.42650
Subject(s) - antimicrobial , antibiotics , hydrazone , minimum inhibitory concentration , pyrazoline , antifungal , chemistry , antibiotic resistance , combinatorial chemistry , microbiology and biotechnology , biology , organic chemistry , biochemistry
Resistance to antibiotics is recognized as one of the biggest threats to human health worldwide. Frequent and unnecessary use of antibiotics has caused infectious agents to adapt to antibiotics and thus drugs have become less effective. The resistance to many antibiotics necessitates the discovery of new antibiotics. In this study, two new and 23 previously reported 2-pyrazoline derivatives and one hydrazone derivative were evaluated for their in vitro antibacterial and antifungal activities.