Open AccessSpectrophotometric Determination of Dopamine in Bulk and Dosage Forms Using 2,4-Dinitrophenylhydrazine
Author(s) -
Mai Ramadan,
Ihab M. Almasri,
Ghada Khayal
Publication year - 2020
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2019.25902
Subject(s) - dopamine , gynecology , medicine
Dopamine (DA) hydrochloride is a sympathomimetic agent used therapeutically for the correction of hemodynamic disorders associated with shock episodes. Although several analytical methods have been described, a spectroscopic assay of DA after chemical derivatization with 2,4-dinitrophenylhydrazine (DNP) is still unexamined. Therefore, the optimization of the reaction parameters and validation of developed method were required.