Open AccessThe Influence of Piperine on the Radioprotective Effect of Curcumin in Irradiated Human Lymphocytes
Author(s) -
Noora Ghelishli,
Arash Ghasemi,
Seyed Jalal Hosseinimehr
Publication year - 2019
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2018.50103
Subject(s) - piperine , curcumin , genotoxicity , chemistry , pharmacology , micronucleus , bioavailability , micronucleus test , toxicity , comet assay , biochemistry , dna damage , biology , dna , organic chemistry
Ionizing radiation (IR) induces DNA damage in normal cells, leading to genotoxicity. The radioprotective effects of co-treatment with curcumin and piperine were investigated against genotoxicity induced by IR in human normal lymphocytes.