Open AccessLevocetirizine Dihydrochloride-Loaded Chitosan Nanoparticles: Formulation and <i>In Vitro</i> Evaluation
Author(s) -
Gülsel Yurtdaş Kırımlıoğlu,
A. Alper Öztürk
Publication year - 2020
Publication title -
turkish journal of pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.241
H-Index - 14
eISSN - 2148-6247
pISSN - 1304-530X
DOI - 10.4274/tjps.galenos.2018.34392
Subject(s) - chitosan , zeta potential , dispersity , bioavailability , materials science , nanoparticle , dialysis tubing , particle size , chemical engineering , chromatography , nanotechnology , chemistry , polymer chemistry , organic chemistry , pharmacology , membrane , medicine , biochemistry , engineering
The aim of the present study was to formulate levocetirizine hydrochloride (LCD)-loaded chitosan nanoparticles at submicron level with high entrapment efficiency and prolonged effect for optimizing the plasma drug concentration enhancing bioavailability.