Open AccessEndometrial CD56+ natural killer cells in women with recurrent implantation failure: An immunohistochemical study
Author(s) -
Gulchin Babayeva,
Yunus Emre Purut,
Burak Giray,
Pembe Oltulu,
Rabia Alakuş,
Mehmet Çolakoğlu
Publication year - 2020
Publication title -
türk jinekoloji ve obstetrik derneði dergisi/türk jinekoloji ve obstetrik derneği dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 9
eISSN - 1307-7007
pISSN - 1307-699X
DOI - 10.4274/tjod.galenos.2020.90359
Subject(s) - implantation failure , endometrium , decidua , medicine , trophoblast , luteal phase , pregnancy , natural killer cell , uterine cavity , natural history , uterus , gynecology , andrology , infertility , biology , fetus , placenta , cytotoxic t cell , hormone , biochemistry , genetics , in vitro
Implantation failure is a multifactorial problem of reproductive medicine. However, the mechanism of this process is still not fully understood. There is increasing evidence that these cases of recurrent implantation failure might have an immunologic background. Uterine natural killer (NK) cells provide immune-modulation at the interface between maternal decidua and the trophoblast. The aim of this study to evaluate whether there was a significant difference in the number of endometrial CD56+ NK between women with a history of recurrent implantation failure and women who had a live birth.