Open AccessPlatelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction
Author(s) -
Gökmen Sukgen,
Aşkı Ellibeş Kaya,
Ebru Karagün,
Eray Çalışkan
Publication year - 2020
Publication title -
türk jinekoloji ve obstetrik derneði dergisi/türk jinekoloji ve obstetrik derneği dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.41
H-Index - 9
eISSN - 1307-7007
pISSN - 1307-699X
DOI - 10.4274/tjod.galenos.2019.23356
Subject(s) - orgasm , sexual function , medicine , platelet rich plasma , sexual dysfunction , sex organ , distress , human sexuality , gynecology , platelet , urology , psychology , clinical psychology , gender studies , sociology , biology , genetics
Objective: To investigate the effect of platelet-rich plasma (PRP) injection to the lower one-third of the anterior vaginal wall on sexual function, orgasm, and genital perception in women with sexual dysfunction. Materials and Methods: Four sessions of PRP were administered to the anterior vaginal wall of 52 female patients with sexual dysfunction and orgasmic disorder [Female Sexual Function Index (FSFI) total score ≤26 orgasmic subdomain score ≤3.75]. Prior to the PRP administrations in each session, the FSFI validated in Turkish, the Female Genital Self-Image Scale (FGSIS), the Female Sexual Distress Scale-Revised (FSDS-R), and Rosenberg’s Self-Esteem Scale were used and in the final follow-up, and the Patient Global Impression of Improvement (PGI-I) was performed and the results were analyzed. Results: Following the application of the PRP, the total FSFI score was observed as 27.88±4.80 and the total score was 26 and above in 50% of the patients (p<0.001). Orgasm subdomain scores were found as 2.11±1.20 before the PRP treatment and 4.48±1.14 afterwards (p<0.001). A significant change was observed in all sub-domains after PRP and it was observed that this change started after the first administration (p<0.001). A statistically significant increase was determined in FGSIS genital perception scores, which was significant between the 1 st and 2 nd months (p<0.001). The FSDS-R scores showed a minimal increase in stress scores as the application number increased, but a statistically significant decrease was observed in the 4th administration (p<0.001). No statistically significant difference was found in Rosenberg Scale scores before and after treatment (p=0.389). High satisfaction was found in PGI-I scores. Conclusion: As a minimally invasive method, PRP administration to the distal anterior vaginal wall may improve female sexuality with high satisfaction.