Kartal Eğitim ve Araştırma Hastanesi Kornea Bankası Donörlerine Ait Speküler Mikroskopi Verileri

Objective: To evaluate the correlation between donor cornea endothelial cell morphology, epidemiological features of the donor and\udtime of death in terms of necessity of specular microscopy (SM) in eye bank.\udMaterials and Methods: SM data acquired from Dr. Lütfi Kırdar Kartal Training and Research Hospital Cornea Bank between 2010\udand 2012 were retrospectively evaluated.\udResults: One thousand one hundred eighty cornea tissues were excised from 606 donors. The mean age of the donors was 40.11±15.51\udyears. Four hundred forty-nine (74.1%) donors were male and 157 (25.9%) donors were female. The mean duration of corneal excision\udwas 1.52±0.6 hours after the time of death. The mean endothelial cell density (ECD) was 2852.07±542.15 cells/mm2 and there was\udno significant difference with respect to gender (p>0.05). According to age groups, the endothelial cell density was highest at age 20\udyears and below, and there was a significant difference compared to the other age groups (p<0.001).The mean cell area (MCA) was\ud367.86±86.30 µm2; the hexagonality rate was 49.29±7.76 (%); the coefficient of variation (CV) was 31.52±6.37 and there was a\udstatistically significant correlation between these variables and age (p<0.001).The MCA was significantly different between males and\udfemales (p<0.05), and there was no correlation between gender-hexagonality or gender-CV (p>0.05). According to the time of death and\udtime of corneal excision, there was no significant difference in ECD, MCA, CV, and hexagonality values between the groups (p>0.05).\udSeventy-nine percent of the donors with endothelial cell density less than 2000cells/mm2 were younger than the age of 60 years and 78%\udof the donors over the 61 ages had a number of endothelial cells more than 2000cells/mm2.\udConclusion: Although morphological parameters of donor cornea show significant correlation with age, distribution of the donors\udwith endothelial cell density less than 2000 cells/mm2 suggests that the evaluation of donor cornea with SM should be performed as a\udstandard procedure before keratoplasty. (Turk J Ophthalmol 2014; 44: 190-5