Open AccessHerpetic Keratouveitis and Trabeculectomy Failure during Infliximab Therapy in a Patient with Behçet’s Disease
Author(s) -
Sirel Gür Güngör,
Leyla Asena,
Ahmet Akman,
Onur Gökmen
Publication year - 2016
Publication title -
türk oftalmoloji dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.654
H-Index - 10
eISSN - 2147-2661
pISSN - 1300-0659
DOI - 10.4274/tjo.59354
Subject(s) - medicine , infliximab , trabeculectomy , behcet's disease , intraocular pressure , glaucoma , surgery , uveitis , ophthalmology , mitomycin c , visual acuity , dermatology , disease
A 51-year-old man was diagnosed with Behçet's disease in 2001. The patient was resistant to all immunosuppressive therapies. After 6 months of infliximab therapy, he presented to our clinic with pain and blurred vision in his right eye. The visual acuity was 20/200 and the intraocular pressure was 35 mmHg in the right eye. Biomicroscopic examination revealed corneal dendritic ulcers and 2+ cells in the anterior chamber in the right eye. The herpetic keratouveitis attack was controlled with antiviral therapy but the patient needed another glaucoma surgery. Trabeculectomy with mitomycin C was performed about halfway through an eight-week interval between two doses of infliximab.