Küçük Hücreli Akciğer Kanserine Bağlı İris Metastazı

Uveal metastasis is the most common intraocular malignancy. In order of frequency, it affects choroid, iris, and ciliary body. We report\udherein the clinicopathologic features and response to therapy in a patient with iris metastasis from a small-cell lung cancer. A 60-yearold\udmale presented with redness and epiphora in his right eye for 4 months. His medical history revealed the presence of a small-cell\udlung cancer that was detected almost a year ago. He had underwent systemic chemotherapy, local radiotherapy, and prophylactic cranial\udradiotherapy. The ophthalmological examination revealed amelanotic, yellow-white nodular mass in the iris stroma in his right eye.\ud27G fine-needle aspiration biopsy was performed under local anesthesia with the primary diagnosis of a metastatic iris tumor.\udCytological analysis was consistent with metastatic iris carcinoma from small-cell lung cancer. He subsequently received a total of 3000\udcGy (in 15 fractions) radiotherapy from frontal field (4x3 cm) with a 7Mev linear accelerator. The tumor regressed completely one\udmonth after therapy and did not recur during the 7-month follow-up. Metastatic iris tumors from small-cell lung cancer are quite rare.\udFine-needle aspiration biopsy is required for the final diagnosis. Local radiotherapy is usually effective in controlling these tumors.\ud(Turk J Ophthalmol 2013; 43: 67-9