Doğum Parametrelerinin Retina Sinir Lifi Tabakası, Makula ve Optik Disk Üzerindeki Etkisi

Pur po se: To investigate the relationships between the birth parameters such as birth weight, gestational age, and birth type and the\udparameters of macula, optic nerve and retinal nerve fiber layer (RNFL) in preschoolers.\udMa te ri al and Met hod: After a broad ophthalmologic examination was performed for every healthy child at age between 3 and 6, the\udchildren were scanned by optical coherence tomography (OCT) for the evaluation of macula, optic disc, and RNFL parameters. The\udrelationships between the birth parameters and OCT parameters were analyzed by Spearman correlation test and Mann Whitney U test.\udRe sults: One hundred and seventy-two eyes of 111 healthy children were evaluated in the study. The mean age of the children was\ud57.48±11.87 months (range: 30-80 months). Forty-eight percent of the children were delivered vaginally and the rest of them - by cesarean\udsection. The negative correlations between gestational age and thicknesses of superior inner and temporal inner macula, and temporal and\udinferior RNFL were statistically significant(r=-0.204, p=0.019; r=-0.203, p=0.020; r=-0.230, p=0.009; r=0.175, p=0.047; respectively).\udWhile the parameters that showed negative correlations with birth weight were superior outer macular thickness, temporal, inferior, and\udaverage RNFL thicknesses and disc area, the parameters that demonstrated positive correlations with birth weight were cup/disc-area and\udhorizontal cup/disc ratios (r=-0.196,p= 0.025; r=-0.317, p< 0.001; r=-0.269, p= 0.002; r=-0.228, p=0.009; r=-0.189, p=0.032; r=0.181,\udp=0.04; r=0.197, p= 0.025,respectively). Optic disc area of the children who were delivered vaginally was larger than that of the children\udwho were delivered by cesarean section and this difference between these two groups was statistically significant (p=0.034).\udDis cus si on: There were significant effects of the birth parameters such as birth weight and gestational age on some parameters of macula\udand optic disc obtained by OCT. It may be thought that the impairment of intrauterine growth could possibly influence optic nerve head\udand macula. (Turk J Ophthalmol 2012; 42: 443-9