Open AccessAkut Ön Üveitli Gözlerde Makuler ve Peripapiller Retina Sinir Lifi Kalınlığı
Author(s) -
Hüseyin Dündar,
Çiğdem Altan,
Berna Başarır,
Hasan Altınkaynak,
Ahmet Demirok,
Ömer Faruk Yılmaz
Publication year - 2012
Publication title -
türk oftalmoloji dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.654
H-Index - 10
eISSN - 2147-2661
pISSN - 1300-0659
DOI - 10.4274/tjo.42.78941
Subject(s) - retina , medicine , physics , ophthalmology , optics
Pur po se: To evaluate the changes in macular and peripapillary retinal nerve fiber layer (RNFL) thickness with optic coherence tomography\ud(OCT) during active inflammation period and after recovery in eyes with acute anterior uveitis (AAU) and to compare them with the\udpatients’ healthy eyes.\udMa te ri al and Met hod: Twenty-two consecutive patients diagnosed with unilateral AAU in the Uvea Department of our hospital were\udincluded in this study. OCT measurements were taken with ‘Stratus OCT fast macular thickness map’ program and ‘fast RNFL thickness’\udprogram. Mean thicknesses of fovea centered 1 mm, 3 mm, 6 mm circles, total macular volume (TMV) and mean RNFL thickness in 3.4 mm\udperipapillary circle were compared between eyes with AAU and healthy eyes. Also, the measurements during the acute attack were compared\udwith measurements of the same eyes after recovery.\udRe sults: There were 14 women and 18 men with a mean age of 37 (range, 20-65) years. Total macular volume, peripapillary RNFL\udthickness and macular thicknesses in 1 mm, 3mm, 6 mm circles were significantly elevated in acutely inflamed eyes as compared with\udhealthy eyes (p<0,05). There were significant differences in the macular thicknesses in the circles of 3 and 6 mm and TMV between acute\udinflammation period and after treatment (p<0.05). However, there were no significant differences in the peripapillary RNFL thickness\udmeasurements (p>0.05). When measurements after recovery were compared with the patients’ healthy eyes, the circle of 3 mm thickness\udand TMV were still significantly higher in the recovered eyes.\udDis cus si on: Although there were no inflammation findings in the posterior segment of eyes with AAU, increased peripapillary RNFL and\udmacular thickness can be detected with OCT. Macular thickness can be decreased after treatment but even when the clinical findings\uddisappear, thickening in the macula can persist for some time. (Turk J Ophthalmol 2012; 42: 20-4