Oküler Tüberküloz II: Tanı ve Tedavi

Recent studies on the clinical importance of tuberculin skin tests (TST), interferon-gamma release assays (IGRAs),\udchest computed tomography (CT) and polymerase chain reaction have provided a new approach to diagnosing ocular\udtuberculosis (TBC). However, both TST and IGRAs cannot distinguish between latent TBC infection and active disease.\udAnother corroborative test in the diagnosis of intraocular TBC is the evaluation of the lungs by either chest radiography\udor CT. Direct evidence for the diagnosis can be obtained by examination of smears and staining for acid-fast organisms,\udcultures of intraocular tissue/fluid for Mycobacterium tuberculosis, and nucleic acid amplification analysis. In recent\udyears, guidelines have been suggested for the diagnosis of intraocular TBC. The current treatment of intraocular TBC\udconsists of use of four drugs (isoniazid, rifampicin, ethambutol and pyrazinamide) taken for a long period of time (total\ud9-15 months). (Turk J Ophthalmol 2011; 41: 182-90