Oküler Onkolojide Biyopsi

Biopsy of a mass lesion implies tissue sampling for histopathologic examination. Tissue sampling can be done with different\udmethodologies. Biopsy techniques include excisional, incisional, core, aspiration biopsies as well as intraoperative biopsy with frozen\udsection and Mohs methods. Sentinel node biopsy is also utilized occasionally for staging purposes of certain tumors. Most of the anteriorly\udlocated and well-delineated tumors can be excised. Incisional biopsy material provides sufficient amount of tissue for pathological\udexamination which is usually obtained from mid or posterior orbital lesions. It is easier to reach the mid and posterior orbit with core or\udfine-needle aspiration biopsy techniques, but these methods provide a limited amount of tissue material. Incisional techniques should\udpreferably be performed on any atypical lesion. Incisional biopsy may promote tumor seeding and lead to local scarring for conjunctiva\udmalignant melanoma. Excisional biopsy is always preferred. If the area of suspected tumor or the area of pigmentation is extensive, map\udbiopsies are made. Sebaceous adenocarcinoma spreads diffusely by pagetoid invasion throughout the conjunctiva. Map biopsy of the\udconjunctiva to determine the extent of involvement of sebaceous adenocarcinoma should be done. Vitreous and chorioretinal biopsy are\udvery useful for differential diagnosis of posterior segment atypical lesions. (Turk J Ophthalmol 2014; 44: Supplement 49-54