Differentiation Potential And Tumorigenic Risk of Rat Bone Marrow Stem Cells Are Affected By Long-Term In Vitro Expansion | Zendy

Erdal Karaöz | Zendy; Filiz Tepeköy | Zendy

Open Access

Differentiation Potential And Tumorigenic Risk of Rat Bone Marrow Stem Cells Are Affected By Long-Term In Vitro Expansion

Author(s) -

Erdal Karaöz,

Filiz Tepeköy

Publication year - 2019

Publication title -

turkish journal of hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.351

H-Index - 16

ISSN - 1300-7777

DOI - 10.4274/tjh.galenos.2019.2019.0100

Subject(s) - medicine , stem cell , in vitro , bone marrow , bone marrow stem cell , cancer research , microbiology and biotechnology , oncology , immunology , biology , genetics

Mesenchymal stem cells (MSCs) have the capacity for extensive expansion and adipogenic, osteogenic, chondrogenic, myogenic, and neural differentiation in vitro. The aim of our study was to determine stemness, differentiation potential, telomerase activity, and ultrastructural characteristics of long-term cultured rat bone marrow (rBM)-MSCs.

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