Open AccessDifferential expression of <i>Hsa-miR-517a/b</i> in placental tissue may contribute to the pathogenesis of preeclampsia
Author(s) -
Mona Amin-Beidokhti,
Hossein Sadeghi,
Reihaneh Pirjani,
Latif Gachkar,
Milad Gholami,
Reza Mirfakhraie
Publication year - 2021
Publication title -
journal of the turkish-german gynecological association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.346
H-Index - 16
eISSN - 1309-0399
pISSN - 1309-0380
DOI - 10.4274/jtgga.galenos.2021.2021.0062
Subject(s) - pathogenesis , preeclampsia , placenta , fetus , real time polymerase chain reaction , andrology , microrna , pregnancy , medicine , endocrinology , biology , gene , genetics
Preeclampsia (PE) is a pregnancy hypertensive disorder that affects both maternal and fetal health. Many studies have investigated possible mechanisms in the pathogenesis of PE although the role of the placenta is undeniable. Evaluation of placental-specific microRNAs may provide additional data about the pathogenic mechanism of PE. This study compared the expression levels of Hsa-miR-517a/b in placental tissues obtained from PE patients and healthy controls.