Open AccessIs Bioavailable Vitamin D Better Than Total Vitamin D to Evaluate Vitamin D Status in Obese Children?
Author(s) -
Gülin Karacan Küçükali,
Özlem Gülbahar,
Şervan Özalkak,
Hasan Dağlı,
Serdar Ceylaner,
Zehra Aycan,
Şenay Savaş Erdeve
Publication year - 2021
Publication title -
jcrpe
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.566
H-Index - 35
eISSN - 1308-5735
pISSN - 1308-5727
DOI - 10.4274/jcrpe.galenos.2020.2021.0230
Subject(s) - vitamin d and neurology , bioavailability , vitamin , medicine , vitamin d binding protein , parathyroid hormone , endocrinology , obesity , calcium , pharmacology
Free hormones are biologically more active in target tissues. Thus, measurement of vitamin D taking into account bioavailability and free vitamin D may be preferable, especially when evidence is contradictory, as in obese children. In order to assess bioavailablity and free vitamin D, using a previously reported formula, vitamin D-binding protein (VDBP) level was measured and VDBP polymorphisms were also evaluated because of variations in binding affinity.