SLC30A8 Gene rs13266634 C/T Polymorphism in Children with Type 1 Diabetes in Tamil Nadu, India | Zendy

Thirunavukkarasu Ramasamy | Zendy; Arthur Asirvatham | Zendy; Ayyappan Chitra | Zendy; Mariakuttikan Jayalakshmi | Zendy

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<i>SLC30A8</i> Gene rs13266634 C/T Polymorphism in Children with Type 1 Diabetes in Tamil Nadu, India

Author(s) -

Thirunavukkarasu Ramasamy,

Arthur Asirvatham,

Ayyappan Chitra,

Mariakuttikan Jayalakshmi

Publication year - 2019

Publication title -

journal of clinical research in pediatric endocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.566

H-Index - 35

eISSN - 1308-5735

pISSN - 1308-5727

DOI - 10.4274/jcrpe.galenos.2018.2018.0195

Subject(s) - odds ratio , genotype , medicine , genetics , allele , type 1 diabetes , transmission disequilibrium test , diabetes mellitus , endocrinology , gene , haplotype , biology

Zinc transporter 8 (ZnT8) is a multi-transmembrane protein situated in the insulin secretory granule of the islets of β-cells and is identified as a novel auto-antigen in type 1 diabetes (T1D). The gene coding for ZnT8, solute carrier family 30 member 8 ( SLC30A8 ) is located on chromosome 8q24.11. This study aimed to identify the association of SLC30A8 rs13266634 C/T gene polymorphism with T1D in a sample of T1D children in Tamil Nadu, India.

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