Open AccessThe Expression of Galectin-3 in Tumor and Cancer-Associated Fibroblasts in Invasive Micropapillary Breast Carcinomas: Relationship with Clinicopathologic Parameters
Author(s) -
Yasemin Çakır,
Canan Kelten Talu,
Özlem Mermut,
Didem Can Trabulus,
Esra Arslan
Publication year - 2021
Publication title -
meme sağlığı dergisi/meme sağlığı dergisi
Language(s) - English
Resource type - Journals
eISSN - 1306-0953
pISSN - 1306-0945
DOI - 10.4274/ejbh.galenos.2021.2021-2-8
Subject(s) - medicine , galectin 3 , pathology , breast cancer , immunohistochemistry , invasive ductal carcinoma , metastasis , h&e stain , stage (stratigraphy) , cancer , oncology , biology , paleontology
Galectin-3 affects tumor progression and cell surface polarization by expressing from the tumor and cancer-associated fibroblasts (CAFs). Therefore, it may have a role on micropapillary carcinomas (IMPC), which have characteristic morphological features. The aim was to investigate the expression levels of Galectin-3 within tumor and peritumoral CAFs in IMPC, and to compare with expression in invasive ductal carcinomas (IDC).