Case Report: Cutaneous Leishmaniasis Misdiagnosed as Pyoderma Gangrenosum | Zendy

Ambra Di Altobrando | Zendy; Cosimo Misciali | Zendy; Beatrice Raone | Zendy; Luciano Attard | Zendy; Valeria Gaspari | Zendy

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Case Report: Cutaneous Leishmaniasis Misdiagnosed as Pyoderma Gangrenosum

Author(s) -

Ambra Di Altobrando,

Cosimo Misciali,

Beatrice Raone,

Luciano Attard,

Valeria Gaspari

Publication year - 2020

Publication title -

american journal of tropical medicine and hygiene

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.015

H-Index - 151

eISSN - 1476-1645

pISSN - 0002-9637

DOI - 10.4269/ajtmh.20-0735

Subject(s) - pyoderma gangrenosum , medicine , dermatology , crohn's disease , etiology , inflammatory bowel disease , disease , cutaneous leishmaniasis , leishmaniasis , pathology

With an estimated prevalence of 0.7%, pyoderma gangrenosum (PG) is the most frequent type of reactive skin lesions seen in the setting of inflammatory bowel disease, together with metastatic Crohn’s disease. However, in the case of persistent cutaneous ulcerations in patients with Crohn’s disease under biologic and/or immunosuppressive therapy, infectious or malignant etiologies should be excluded. We report a case of multiple difficult-to-treat skin ulcerations due to Leishmania in a patient with Crohn’s disease treated with antitumor necrosis factor-alpha drugs, misinterpreted for a long time as PG.

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