Open AccessThe Indirect Hemagglutination Test for Malaria
Author(s) -
Mathews Hm,
Fried Ja,
Kagan Ig
Publication year - 1975
Publication title -
the american journal of tropical medicine and hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.015
H-Index - 151
eISSN - 1476-1645
pISSN - 0002-9637
DOI - 10.4269/ajtmh.1975.24.417
Subject(s) - hemagglutination , heterologous , malaria , plasmodium vivax , virology , antigen , plasmodium falciparum , biology , antibody , microbiology and biotechnology , immunology , biochemistry , gene
Soluble antigens were prepared from Plasmodium falciparum and P. vivax and were evaluated in the indirect hemagglutination test. These antigens, attached to aldehyde-fixed type "O" erythrocytes, detected antibodies in more than 91% of infections with the homologous Plasmodium species. Detection rates in infections caused by the heterologous species ranged from 72% to 76%. Positive reactions occurred in less than 2% of sera from persons without malaria infection.