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Case Report: Coinfection with Rickettsia monacensis and Orientia tsutsugamushi
Author(s) -
Seok Won Kim,
ChoonMee Kim,
DongMin Kim,
Na Ra Yun
Publication year - 2019
Publication title -
american journal of tropical medicine and hygiene
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.015
H-Index - 151
eISSN - 1476-1645
pISSN - 0002-9637
DOI - 10.4269/ajtmh.18-0631
Subject(s) - orientia tsutsugamushi , scrub typhus , eschar , rickettsia , biology , rickettsiosis , virology , rash , spotted fever , microbiology and biotechnology , polymerase chain reaction , coinfection , medicine , dermatology , gene , pathology , virus , genetics
Rickettsia monacensis and Orientia tsutsugamushi are bacteria of the family Rickettsiaceae, which causes fever, rash, and eschar formation; outdoor activities are a risk factor for Rickettsiaceae infection. A 75-year-old woman presented with fever, rash, and eschar and was confirmed as being scrub typhus based on a nested-polymerase chain reaction (N-PCR) test for a 56-kDa gene of O. tsutsugamushi ; the genome was identified as the Boryong genotype. In addition, a pan-Rickettsia real-time PCR test was positive and a N-PCR test using a Rickettsia -specific partial outer membrane protein A (rOmpA) confirmed R. monacensis . This is the first case wherein a patient suspected of having scrub typhus owing to the presence of rash and eschar was also found to be coinfected with O. tsutsugamushi and R. monacensis based on molecular testing.

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