Open AccessHepatocellular carcinoma: Surgeon's view on latest findings and future perspectives
Author(s) -
Jan E. Slotta,
Otto Kollmar,
Volker Ellenrieder,
B. Michael Ghadimi,
Kia Homayounfar
Publication year - 2015
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v7.i9.1168
Subject(s) - medicine , hepatocellular carcinoma , malignancy , therapeutic modalities , case fatality rate , modalities , curative treatment , oncology , general surgery , intensive care medicine , epidemiology , disease , social science , sociology
Hepatocellular carcinoma (HCC) is the most common liver-derived malignancy with a high fatality rate. Risk factors for the development of HCC have been identified and are clearly described. However, due to the lack of tumor-specific symptoms, HCC are diagnosed at progressed tumor stages in most patients, and thus curative therapeutic options are limited. The focus of this review is on surgical therapeutic options which can be offered to patients with HCC with special regard to recent findings, not exclusively focused on surgical therapy, but also to other treatment modalities. Further, potential promising future perspectives for the treatment of HCC are discussed.