Open AccessDietary supplements and pediatric non-alcoholic fatty liver disease: Present and the future
Author(s) -
Mehran Rahimlou,
Hoda Ahmadnia,
Azita Hekmatdoost
Publication year - 2015
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v7.i25.2597
Subject(s) - medicine , fatty liver , obesity , disease , insulin resistance , incidence (geometry) , metabolic syndrome , steatohepatitis , chronic liver disease , cirrhosis , physics , optics
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children. High prevalence of pediatric obesity and sedentary lifestyle has augmented the incidence of NAFLD in children. Obesity is associated with an increased risk of NAFLD through various mechanisms such as intensification of insulin resistance and increased levels of inflammatory markers. There is no approved medical intervention for treatment of pediatric NAFLD; the only proven strategy in management of pediatric NAFLD is lifestyle modification. Recently, the effects of nutritional supplements have been examined in the management of pediatric NAFLD. The purpose of this review is to summarize the studies evaluating the effects of nutritional supplements on pediatric NAFLD and explain the future direction in this field.