Open AccessRenal failure in cirrhosis: Emerging concepts
Author(s) -
Paulo Lisboa Bittencourt,
Alberto Queiróz Farias,
Carlos Terra
Publication year - 2015
Publication title -
world journal of hepatology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v7.i21.2336
Subject(s) - medicine , hepatorenal syndrome , acute kidney injury , cirrhosis , ascites , intensive care medicine , gastroenterology
Acute renal failure, now termed acute kidney injury (AKI), is frequently found in patients with cirrhosis. The occurrence of AKI, irrespective of the underlying cause, is associated with reduced in-hospital, 3-mo and 1-year survival. Hepatorenal syndrome is associated with the worst outcome among AKI patients with cirrhosis. Several definitions for AKI that have been proposed are outlined and evaluated in this paper. Among these, the International Club for Ascites-AKI criteria substantially strengthen the quality of early diagnosis and intervention according to underlying cause of AKI.