Open AccessManagement of hepatocellular carcinoma: Predictive value of immunohistochemical markers for postoperative survival
Author(s) -
Zhaojian Niu,
Xiao-Jun Niu,
Mei Wang
Publication year - 2015
Publication title -
world journal of hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.913
H-Index - 55
ISSN - 1948-5182
DOI - 10.4254/wjh.v7.i1.7
Subject(s) - medicine , hepatocellular carcinoma , incidence (geometry) , immunohistochemistry , oncology , hepatectomy , overall survival , predictive value , hepatocellular cancer , gastroenterology , resection , surgery , physics , optics
Hepatocellular carcinoma (HCC) accounts for over 90% of all primary liver cancers. With an ever increasing incidence trend year by year, it has become the third most common cause of death from cancer worldwide. Hepatic resection is generally considered to be one of the most effective therapies for HCC patients, however, there is a high risk of recurrence in postoperative HCC. In clinical practice, there exists an urgent need for valid prognostic markers to identify patients with prognosis, hence the importance of studies on prognostic markers in improving the prediction of HCC prognosis. This review focuses on the most promising immunohistochemical prognostic markers in predicting the postoperative survival of HCC patients.